LCE2B

Across TCGA patient cohorts, LCE2B mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LCE2B-associated genes across cancer lineages are Erythrocytes, CMP, and CD4+ T-cells. Each is linked with LCE2B in more than 1 cancer types. Because this analysis shows association rather than direction, both LCE2B-to-partner and partner-to-LCE2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Erythrocytes grouped by LCE2B-low versus LCE2B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LCE2B→partner) and Y-score (partner→LCE2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Erythrocytes →	+0.033	+2.879	.010	.033	3	2
UCEC	CMP →	+0.042	+2.180	.008	.036	2	2
UCEC	CD4+ T-cells →	+0.005	+4.744	<.001	.040	3	1
UCEC	lymphatic Endothelial cells →	-0.026	-3.268	.035	.011	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Erythrocytes by LCE2B expression — UCEC

Explore this box plot interactively →