Cross-omicsRNA → MUTATIONCell-linePairwise association · TCGA cohorts
Across TCGA cell cohorts, LCE2B RNA expression is significantly associated with the mutation status of many other genes, with 62 significant associations in total. SOFT_TISSUE shows the largest number of these associations.
The most reproducible LCE2B-associated genes across cancer lineages are DNAH3, DYNC1H1, and XDH. Each is linked with LCE2B in more than 1 cancer types. Because this analysis shows association rather than direction, both LCE2B-to-partner and partner-to-LCE2B results are reported.
Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNAH3 grouped by LCE2B-low versus LCE2B-high in PANCREAS.
RNA expression associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (LCE2B→partner) and Y-score (partner→LCE2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.