LCE2B

RNA expression — cross-omics
Cross-omicsRNA → MUTATIONCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, LCE2B RNA expression is significantly associated with the mutation status of many other genes, with 62 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible LCE2B-associated genes across cancer lineages are DNAH3, DYNC1H1, and XDH. Each is linked with LCE2B in more than 1 cancer types. Because this analysis shows association rather than direction, both LCE2B-to-partner and partner-to-LCE2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNAH3 grouped by LCE2B-low versus LCE2B-high in PANCREAS.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LCE2B→partner) and Y-score (partner→LCE2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PANCREASDNAH3 →+3.554+0.022.003<.00132
PANCREASDYNC1H1 →+3.554+0.022.003<.00132
SOFT_TISSUEXDH →+4.392+0.024.004<.00132
CNSKRT3 →+5.357+0.060.001<.00132
PANCREASADAMTS15 →+4.139+0.031.001<.00131
PANCREASNAV2 →+2.817+0.016.009.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 62 associations by consensus.

DNAH3 by LCE2B expression — PANCREAS

Box plot of DNAH3 in LCE2B-low vs LCE2B-high samples in PANCREAS.

Explore this box plot interactively →

Exploration