LCE2B

Across TCGA cell cohorts, LCE2B mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible LCE2B-associated genes across cancer lineages are OCM2, GLRA4, and DPPA5. Each is linked with LCE2B in more than 1 cancer types. Because this analysis shows association rather than direction, both LCE2B-to-partner and partner-to-LCE2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OCM2 grouped by LCE2B-low versus LCE2B-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LCE2B→partner) and Y-score (partner→LCE2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OCM2 →	+0.026	+4.078	<.001	.009	3	1
LUNG_NSCLC_LUAD	GLRA4 →	+0.158	+3.544	<.001	.009	3	1
LUNG_NSCLC_LUAD	DPPA5 →	+0.042	+3.544	.002	.009	3	1
LUNG_NSCLC_LUAD	USP17L4 →	+0.030	+3.760	<.001	.008	3	1
LUNG_NSCLC_LUAD	KRTAP10-5 →	+0.011	+4.078	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

OCM2 by LCE2B expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →