Across TCGA cell cohorts, LCE2A RNA expression is significantly associated with the go_rna of many other GO terms, with 814 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible LCE2A-associated GO terms across cancer lineages are Maintenance of apical/basal cell polarity, Maintenance of epithelial cell apical/basal polarity, and Negative regulation of bone mineralization involved in bone maturation. Each is linked with LCE2A in more than 3 cancer types. Because this analysis shows association rather than direction, both LCE2A-to-partner and partner-to-LCE2A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LCE2A→partner) and Y-score (partner→LCE2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Maintenance of apical/basal cell polarity →	+0.089	+0.887	.001	<.001	3	4
SKIN	Maintenance of epithelial cell apical/basal polarity →	+0.089	+0.887	.001	<.001	3	4
SKIN	Negative regulation of bone mineralization involved in bone maturation →	+0.821	+1.047	.002	<.001	3	3
SKIN	Deactivation of mitotic spindle assembly checkpoint →	+0.212	+1.215	<.001	<.001	3	3
SKIN	Inhibitory synapse assembly →	-0.101	-1.207	<.001	<.001	3	3
SKIN	Negative regulation of protein localization to cell surface →	+0.086	+0.766	.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 814 associations by consensus.

Exploration

LCE2A survival (RNA) · tumor vs normal (RNA) · all LCE2A data types