Across TCGA patient cohorts, LCE1E mutation is significantly associated with the RNA expression of many other genes, with 476 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LCE1E-associated genes across cancer lineages are LSM4, MED27, and TOMM34. Each is linked with LCE1E in more than 1 cancer types. Because this analysis shows association rather than direction, both LCE1E-to-partner and partner-to-LCE1E results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LCE1E→partner) and Y-score (partner→LCE1E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	LSM4 →	+0.608	+3.379	<.001	.005	3	2
SKCM	MED27 →	+0.603	+3.328	<.001	.005	3	2
SKCM	TOMM34 →	+0.643	+3.226	.002	.009	3	2
SKCM	SLC66A1 →	+0.751	+3.341	<.001	.005	3	2
SKCM	LINC00239 →	+0.959	+3.341	.002	.005	3	2
UCEC	ARRDC1-AS1 →	+0.489	+3.332	.004	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 476 associations by consensus.

Exploration

LCE1E survival (RNA) · tumor vs normal (RNA) · all LCE1E data types