Across TCGA pan-cancer cohorts, LCE1E RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated LCE1E data layer compared with 2 for mutation status.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher LCE1E RNA is associated with better overall survival. In most high-consensus cancer types, elevated LCE1E expression acts as an unfavorable survival marker, although some lineages such as HNSC and LGG show a favorable association.
HNSC, KIRP, and LGG are the cancer types where LCE1E RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.