LCE1C

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LCE1C mutation is significantly associated with the RNA expression of many other genes, with 253 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LCE1C-associated genes across cancer lineages are LINC01553, RNU6-222P, and RPL36AP55. Each is linked with LCE1C in more than 1 cancer types. Because this analysis shows association rather than direction, both LCE1C-to-partner and partner-to-LCE1C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LCE1C→partner) and Y-score (partner→LCE1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMLINC01553 →+0.007+3.330.007.00432
STADRNU6-222P →+0.728+3.657.001.00732
STADRPL36AP55 →+0.285+3.660<.001.00732
STADCOX6CP13 →+0.321+3.763.006.00332
STADRNA5SP24 →+0.564+3.310<.001.00432
LUSCMIR5586 →+0.214+5.333<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 253 associations by consensus.

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