Q-omics provides the consensus-scored MIR5586 profile across patient tissues and cancer cell-line models. MIR5586 expression is associated with patient survival in 5 of 34 cancer types, with the highest sampling consensus in LUSC. Among the 18 cancer types available for tumor–normal comparison, MIR5586 is differentially expressed in 1, with the highest sampling consensus in PRAD. Additionally, MIR5586 RNA expression shows 7,755 significant gene co-expression associations, with the highest sampling consensus in BRCA. Together, these results highlight LUSC, PRAD, and BRCA as cancer lineages where MIR5586 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR5586 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR5586 survival associations across molecular data types. MIR5586 RNA expression shows survival associations in the most cancer types (5). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR5586 RNA expression–survival associations across cancer types. High MIR5586 expression shows unfavorable associations in LUSC, MESO, LAML, HNSC and SARC. The LUSC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .012). Together, the overview and detailed table identify LUSC as the clearest survival context for MIR5586 RNA expression.
This table summarizes MIR5586 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in PRAD for RNA.
This table ranks reproducible tumor–normal expression differences for MIR5586. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR5586 shows higher tumor expression in PRAD. The PRAD box plot shows higher MIR5586 RNA expression in tumor versus normal tissue (log2 FC = +0.083, t-test p = .047).
This table shows molecular features associated with MIR5586 in patient tissues and cancer cell lines. In patient samples, MIR5586 shows the broadest associations at the RNA and protein expression levels, with BRCA recurring as the lineage with the largest associated feature set.
