Across TCGA patient cohorts, LBX1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,182 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible LBX1-associated GO terms across cancer lineages are Mammary gland epithelial cell proliferation, Semi-lunar valve development, and Glutamatergic neuron differentiation. Each is linked with LBX1 in more than 8 cancer types. Because this analysis shows association rather than direction, both LBX1-to-partner and partner-to-LBX1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LBX1→partner) and Y-score (partner→LBX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mammary gland epithelial cell proliferation →	+0.072	+0.118	<.001	<.001	3	9
TGCT	Semi-lunar valve development →	+0.050	+0.568	<.001	<.001	3	8
TGCT	Glutamatergic neuron differentiation →	-0.072	-0.536	<.001	<.001	3	8
TGCT	Negative regulation of transferase activity →	+0.020	+0.551	<.001	.001	3	8
TGCT	Respiratory system development →	+0.030	+0.614	<.001	<.001	3	8
TGCT	Cell surface receptor signaling pathway involved in heart development →	+0.060	+0.590	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,182 associations by consensus.

Exploration

LBX1 survival (RNA) · tumor vs normal (RNA) · all LBX1 data types