LBX1

Across TCGA patient cohorts, LBX1 protein abundance is significantly associated with the RNA expression of many other genes, with 216 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LBX1-associated genes across cancer lineages are FYN, CHL1, and MED21. Each is linked with LBX1 in more than 1 cancer types. Because this analysis shows association rather than direction, both LBX1-to-partner and partner-to-LBX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LBX1 versus FYN in OV, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LBX1→partner) and Y-score (partner→LBX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FYN →	+1.431	+1.463	<.001	.001	3	1
OV	CHL1 →	-2.811	-1.531	.005	.001	3	1
OV	MED21 →	+1.126	+1.053	.003	.007	3	1
OV	LSM12 →	-0.616	-1.331	.001	.009	3	1
OV	CA8 →	+2.385	+1.566	<.001	.001	3	1
OV	TRIM73 →	+0.271	+1.323	.007	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 216 associations by consensus.

LBX1 vs FYN — OV

Explore this scatter interactively →