LBX1

Across TCGA patient cohorts, LBX1 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LBX1-associated genes across cancer lineages are NK cells and Osteoblast. Each is linked with LBX1 in more than 1 cancer types. Because this analysis shows association rather than direction, both LBX1-to-partner and partner-to-LBX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NK cells grouped by LBX1-low versus LBX1-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LBX1→partner) and Y-score (partner→LBX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	NK cells →	+0.004	+5.012	<.001	.003	3	1
STAD	Osteoblast →	+0.030	+3.254	.001	.019	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

NK cells by LBX1 expression — STAD

Explore this box plot interactively →