LBP

Across TCGA patient cohorts, LBP protein abundance is significantly associated with the RNA expression of many other genes, with 11,761 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LBP-associated genes across cancer lineages are SERPINE1, MEDAG, and CRISPLD2. Each is linked with LBP in more than 8 cancer types. Because this analysis shows association rather than direction, both LBP-to-partner and partner-to-LBP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LBP versus SERPINE1 in GBM, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LBP→partner) and Y-score (partner→LBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SERPINE1 →	+1.758	+1.067	<.001	<.001	3	9
GBM	MEDAG →	+1.319	+0.824	<.001	<.001	3	8
UCEC	CRISPLD2 →	+0.912	+0.661	.001	.001	3	8
CCRCC	VGLL3 →	+0.864	+0.824	<.001	<.001	3	8
UCEC	MYL9 →	+1.447	+0.833	<.001	<.001	3	7
COAD	FLT1 →	+0.922	+0.815	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,761 associations by consensus.

LBP vs SERPINE1 — GBM

Explore this scatter interactively →