LBP

Across TCGA pan-cancer cohorts, LBP RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated LBP data layer compared with 3 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher LBP RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LBP expression acts as an unfavorable survival marker, although some lineages such as ESCA and COAD show a favorable association.

STAD, KIRP, and KIRC are the cancer types where LBP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	DFS	Quartile	All	0.252	0.505	<.001	89	view →
KIRP	OS	Median	All	0.567	0.819	<.001	63	view →
KIRC	DFS	Median	All	0.549	0.694	<.001	57	view →
KICH	OS	Quartile	All	0.614	0.972	.004	56	view →
CESC	OS	Median	IV	0.092	0.541	.003	50	view →
CHOL	OS	Median	II,III,IV	0.243	0.732	.005	46	view →
LUSC	DFS	Tertile	II,III,IV	0.617	0.802	.002	40	view →
LUAD	DFS	Median	All	0.742	0.838	<.001	33	view →
ACC	OS	Tertile	II,III,IV	0.704	1.000	.003	33	view →
BRCA	OS	Median	IV	0.352	0.810	.006	25	view →
LGG	OS	Tertile	All	0.403	0.692	.004	22	view →
UVM	OS	Median	All	0.729	0.918	.006	21	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

LBP–STAD (DFS)

Open the STAD breakdown →