LBP

Across TCGA cell cohorts, LBP RNA expression is significantly associated with the go_rna of many other GO terms, with 892 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LBP-associated GO terms across cancer lineages are Energy derivation by oxidation of organic compounds, Positive regulation of cellular respiration, and Cytoplasmic translation. Each is linked with LBP in more than 4 cancer types. Because this analysis shows association rather than direction, both LBP-to-partner and partner-to-LBP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Energy derivation by oxidation of organic compounds grouped by LBP-low versus LBP-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LBP→partner) and Y-score (partner→LBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Energy derivation by oxidation of organic compounds →	+0.043	+0.040	<.001	.008	3	4
LIVER	Positive regulation of cellular respiration →	+0.154	+1.249	.001	.002	3	4
SKIN	Cytoplasmic translation →	+0.064	+0.057	<.001	.006	3	4
SKIN	Host-mediated suppression of symbiont invasion →	+0.118	+0.052	<.001	.009	2	5
BLOOD_Leukemia	Viral process →	+0.030	+0.068	.008	.008	3	4
LARGE_INTESTINE	Regulation of natural killer cell mediated immune response to tumor cell →	+0.109	+0.026	.009	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 892 associations by consensus.

Energy derivation by oxidation of organic compounds by LBP expression — SKIN

Explore this box plot interactively →