Across TCGA patient cohorts, LBH protein abundance is significantly associated with the RNA expression of many other genes, with 13,532 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LBH-associated genes across cancer lineages are DPT, JAM2, and IGFBP7. Each is linked with LBH in more than 8 cancer types. Because this analysis shows association rather than direction, both LBH-to-partner and partner-to-LBH results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LBH→partner) and Y-score (partner→LBH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DPT →	+1.302	+0.524	<.001	<.001	3	8
UCEC	JAM2 →	+0.837	+0.425	<.001	.001	3	8
OV	IGFBP7 →	+0.866	+0.357	.001	.001	3	8
COAD	MSRB3 →	+1.123	+0.666	.001	.005	2	9
CCRCC	VGLL3 →	+0.885	+0.305	<.001	<.001	3	8
HNSC	LINC00702 →	+0.653	+0.361	.006	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,532 associations by consensus.

Exploration

LBH survival (RNA) · tumor vs normal (RNA) · all LBH data types