LAX1

Across TCGA patient cohorts, LAX1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,740 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LAX1-associated genes across cancer lineages are IGHJ1, IGHD3-16, and IGHD3-10. Each is linked with LAX1 in more than 4 cancer types. Because this analysis shows association rather than direction, both LAX1-to-partner and partner-to-LAX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LAX1 versus IGHJ1 in CCRCC, with a Pearson correlation of 0.98.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LAX1→partner) and Y-score (partner→LAX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	IGHJ1 →	+6.005	+3.341	.003	<.001	2	5
CCRCC	IGHD3-16 →	+4.465	+3.379	.002	.001	2	5
CCRCC	IGHD3-10 →	+5.025	+3.341	<.001	<.001	3	4
CCRCC	IGHD6-6 →	+6.285	+3.341	.005	<.001	3	4
CCRCC	TOMM20P3 →	+1.540	+3.341	.003	<.001	3	4
HNSC	SLA2 →	+0.988	+1.012	.007	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,740 associations by consensus.

LAX1 vs IGHJ1 — CCRCC

Explore this scatter interactively →