LAX1

Across TCGA cell cohorts, LAX1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,582 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LAX1-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Proton motive force-driven mitochondrial ATP synthesis, and Mitochondrial electron transport, NADH to ubiquinone. Each is linked with LAX1 in more than 7 cancer types. Because this analysis shows association rather than direction, both LAX1-to-partner and partner-to-LAX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by LAX1-low versus LAX1-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LAX1→partner) and Y-score (partner→LAX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Negative regulation of myoblast fusion →	+0.075	+0.066	<.001	.001	3	8
STOMACH	Proton motive force-driven mitochondrial ATP synthesis →	+0.112	+0.063	.006	.004	2	8
LUNG_NSCLC_LUAD	Mitochondrial electron transport, NADH to ubiquinone →	+0.066	+0.022	<.001	.009	3	7
STOMACH	ATP biosynthetic process →	+0.107	+0.063	.003	.003	2	8
OESOPHAGUS	mRNA catabolic process →	+0.063	+0.107	.004	.005	3	7
CNS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.072	+0.055	<.001	.005	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,582 associations by consensus.

Negative regulation of myoblast fusion by LAX1 expression — CNS

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