LATS2-AS1

Across TCGA pan-cancer cohorts, LATS2-AS1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of LATS2-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where LATS2-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types LATS2-AS1 is over-expressed in tumor, although a few such as PAAD and KICH show the opposite, repressed pattern.

PAAD and KICH are the cancer types where LATS2-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LATS2-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
PAAD	Female	All	−0.155	.047	2	view →
KICH	All	All	−0.027	.029	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

LATS2-AS1–PAAD

Open the PAAD breakdown →