LATS1

Across TCGA patient cohorts, LATS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,461 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LATS1-associated proteins across cancer lineages are LATS1_S613, SCAF8, and PPIL4. Each is linked with LATS1 in more than 5 cancer types. Because this analysis shows association rather than direction, both LATS1-to-partner and partner-to-LATS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LATS1 versus LATS1_S613 in BRCA, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LATS1→partner) and Y-score (partner→LATS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LATS1_S613 →	+0.504	+0.794	<.001	<.001	3	6
BRCA	SCAF8 →	+0.230	+0.700	<.001	<.001	3	6
GBM	PPIL4 →	+0.259	+0.364	<.001	<.001	3	6
LSCC	DHX9 →	+0.306	+0.490	<.001	<.001	3	5
LSCC	GATAD2B →	+0.348	+0.559	<.001	<.001	3	5
BRCA	VTA1 →	+0.382	+0.750	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,461 associations by consensus.

LATS1 vs LATS1_S613 — BRCA

Explore this scatter interactively →