LATS1

Across TCGA patient cohorts, LATS1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,996 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LATS1-associated genes across cancer lineages are VTA1, FBXO30, and NUP43. Each is linked with LATS1 in more than 4 cancer types. Because this analysis shows association rather than direction, both LATS1-to-partner and partner-to-LATS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LATS1 versus VTA1 in LSCC, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LATS1→partner) and Y-score (partner→LATS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	VTA1 →	+0.492	+0.211	<.001	<.001	3	5
LSCC	FBXO30 →	+0.517	+0.242	<.001	<.001	3	4
BRCA	NUP43 →	+0.479	+0.326	.002	<.001	3	4
LSCC	NDUFAF4 →	+0.448	+0.196	<.001	<.001	3	4
LSCC	KATNA1 →	+0.416	+0.193	<.001	<.001	3	4
LSCC	SNORA33 →	+0.611	+0.199	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,996 associations by consensus.

LATS1 vs VTA1 — LSCC

Explore this scatter interactively →