Across TCGA patient cohorts, LAT mutation is significantly associated with the RNA expression of many other genes, with 249 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LAT-associated genes across cancer lineages are RNU7-11P, LINC02210-CRHR1, and CLDND2. Each is linked with LAT in more than 2 cancer types. Because this analysis shows association rather than direction, both LAT-to-partner and partner-to-LAT results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LAT→partner) and Y-score (partner→LAT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU7-11P →	+1.372	+5.145	<.001	.007	3	3
CESC	LINC02210-CRHR1 →	+0.098	+4.824	<.001	<.001	3	2
UCEC	CLDND2 →	+0.740	+3.209	.001	.009	3	2
COAD	RNU6-128P →	+1.077	+6.003	<.001	.002	3	2
COAD	MTCO3P23 →	+0.395	+5.435	.002	.005	3	2
COAD	MIR3908 →	+0.530	+7.734	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 249 associations by consensus.

Exploration

LAT survival (RNA) · tumor vs normal (RNA) · all LAT data types