LAS1L

Across TCGA patient cohorts, LAS1L RNA expression is significantly associated with the protein abundance of many other proteins, with 17,239 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LAS1L-associated proteins across cancer lineages are NONO, STAG2, and MSH2. Each is linked with LAS1L in more than 8 cancer types. Because this analysis shows association rather than direction, both LAS1L-to-partner and partner-to-LAS1L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LAS1L versus NONO in GBM, with a Pearson correlation of 0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LAS1L→partner) and Y-score (partner→LAS1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NONO →	+0.227	+0.349	<.001	<.001	3	9
GBM	STAG2 →	+0.354	+0.415	<.001	<.001	3	8
LSCC	MSH2 →	+0.431	+0.504	<.001	<.001	3	8
GBM	THOC1 →	+0.313	+0.368	<.001	<.001	3	7
GBM	THOC2 →	+0.311	+0.365	<.001	<.001	3	7
GBM	SMC1A →	+0.315	+0.349	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,239 associations by consensus.

LAS1L vs NONO — GBM

Explore this scatter interactively →