LAS1L

Across TCGA cell cohorts, LAS1L RNA expression is significantly associated with the go_rna of many other GO terms, with 4,231 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible LAS1L-associated GO terms across cancer lineages are DNA replication initiation, Mitotic spindle elongation, and Mitotic spindle midzone assembly. Each is linked with LAS1L in more than 18 cancer types. Because this analysis shows association rather than direction, both LAS1L-to-partner and partner-to-LAS1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication initiation grouped by LAS1L-low versus LAS1L-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LAS1L→partner) and Y-score (partner→LAS1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA replication initiation →	+0.212	+0.900	<.001	<.001	3	19
BONE	Mitotic spindle elongation →	+0.259	+0.767	.006	.001	3	18
BONE	Mitotic spindle midzone assembly →	+0.259	+0.767	.006	.001	3	18
PANCREAS	rRNA metabolic process →	+0.116	+1.313	<.001	<.001	3	17
OVARY	Spindle elongation →	+0.262	+1.047	<.001	<.001	3	17
BONE	DNA replication checkpoint signaling →	+0.168	+0.669	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,231 associations by consensus.

DNA replication initiation by LAS1L expression — BONE

Explore this box plot interactively →