LARS2-AS1

Across TCGA patient cohorts, LARS2-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,240 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LARS2-AS1-associated proteins across cancer lineages are TOP2B, DHX30, and SUPT16H. Each is linked with LARS2-AS1 in more than 5 cancer types. Because this analysis shows association rather than direction, both LARS2-AS1-to-partner and partner-to-LARS2-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LARS2-AS1 versus TOP2B in GBM, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LARS2-AS1→partner) and Y-score (partner→LARS2-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TOP2B →	+0.552	+0.500	<.001	<.001	3	6
UCEC	DHX30 →	+0.320	+0.703	<.001	<.001	3	6
GBM	SUPT16H →	+0.430	+0.396	<.001	<.001	3	5
GBM	GTF3C3 →	+0.252	+0.376	<.001	<.001	3	5
LSCC	DHX9 →	+0.198	+0.418	.002	<.001	3	4
GBM	TRADD →	-0.290	-0.312	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,240 associations by consensus.

LARS2-AS1 vs TOP2B — GBM

Explore this scatter interactively →