LARP6

Across TCGA cell cohorts, LARP6 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,234 significant associations in total. BONE shows the largest number of these associations.

The most reproducible LARP6-associated GO terms across cancer lineages are Positive regulation of focal adhesion assembly, Positive regulation of collagen metabolic process, and Positive regulation of collagen biosynthetic process. Each is linked with LARP6 in more than 13 cancer types. Because this analysis shows association rather than direction, both LARP6-to-partner and partner-to-LARP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of focal adhesion assembly grouped by LARP6-low versus LARP6-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LARP6→partner) and Y-score (partner→LARP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of focal adhesion assembly →	+0.233	+1.915	<.001	<.001	3	14
PANCREAS	Positive regulation of collagen metabolic process →	+0.160	+1.135	.001	.008	2	13
PANCREAS	Positive regulation of collagen biosynthetic process →	+0.149	+1.197	<.001	.001	3	12
BONE	Regulation of focal adhesion assembly →	+0.176	+1.805	<.001	<.001	3	11
BONE	Regulation of cell-matrix adhesion →	+0.158	+1.758	<.001	<.001	3	11
BONE	Positive regulation of intracellular transport →	+0.067	+1.739	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,234 associations by consensus.

Positive regulation of focal adhesion assembly by LARP6 expression — BONE

Explore this box plot interactively →