LARP4B

Across TCGA cell cohorts, LARP4B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,138 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible LARP4B-associated GO terms across cancer lineages are Regulation of translation at postsynapse, modulating synaptic transmission, Regulation of DNA repair, and Positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Each is linked with LARP4B in more than 11 cancer types. Because this analysis shows association rather than direction, both LARP4B-to-partner and partner-to-LARP4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of translation at postsynapse, modulating synaptic transmission grouped by LARP4B-low versus LARP4B-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LARP4B→partner) and Y-score (partner→LARP4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Regulation of translation at postsynapse, modulating synaptic transmission →	+0.111	+0.641	<.001	<.001	3	12
LARGE_INTESTINE	Regulation of DNA repair →	+0.056	+0.879	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.174	+1.071	<.001	<.001	3	11
LARGE_INTESTINE	Regulation of TORC2 signaling →	+0.097	+0.932	<.001	<.001	3	11
BLOOD_Lymphoma	CAMP/PKA signal transduction →	+0.148	+1.348	<.001	<.001	3	11
SOFT_TISSUE	Subtelomeric heterochromatin formation →	+0.098	+0.709	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,138 associations by consensus.

Regulation of translation at postsynapse, modulating synaptic transmission by LARP4B expression — BLOOD_Leukemia

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