LARP1B

Across TCGA cell cohorts, LARP1B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,065 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LARP1B-associated GO terms across cancer lineages are Nuclear pore complex assembly, Centrosome duplication, and Negative regulation of transcription by RNA polymerase I. Each is linked with LARP1B in more than 8 cancer types. Because this analysis shows association rather than direction, both LARP1B-to-partner and partner-to-LARP1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear pore complex assembly grouped by LARP1B-low versus LARP1B-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LARP1B→partner) and Y-score (partner→LARP1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Nuclear pore complex assembly →	+0.108	+0.861	.001	<.001	3	9
LARGE_INTESTINE	Centrosome duplication →	+0.093	+0.895	<.001	.001	3	9
LARGE_INTESTINE	Negative regulation of transcription by RNA polymerase I →	+0.114	+0.687	<.001	<.001	3	9
SOFT_TISSUE	Establishment or maintenance of monopolar cell polarity →	-0.108	-0.503	.003	.003	3	8
LARGE_INTESTINE	DNA alkylation repair →	+0.085	+0.661	<.001	<.001	3	8
OVARY	Regulation of SREBP signaling pathway →	+0.088	+0.852	.002	<.001	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,065 associations by consensus.

Nuclear pore complex assembly by LARP1B expression — LARGE_INTESTINE

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