LARP1B

Across TCGA pan-cancer cohorts, LARP1B RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of LARP1B’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where LARP1B RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LARP1B is over-expressed in tumor, although a few such as THCA and LIHC show the opposite, repressed pattern.

STAD, LUAD, and THCA are the cancer types where LARP1B tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LARP1B RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	All	All	+0.465	<.001	10	view →
LUAD	Male	All	+0.580	<.001	9	view →
THCA	All	All	−0.329	<.001	8	view →
BRCA	All	II,III,IV	+0.498	<.001	4	view →
KIRC	All	All	+0.177	.016	3	view →
UCEC	All	III,IV	+0.635	.049	2	view →
PRAD	All	All	+0.427	<.001	2	view →
COAD	Male	All	+0.373	.005	2	view →
LUSC	Male	II,III,IV	+0.322	.027	2	view →
LIHC	All	All	−0.319	.006	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

LARP1B–STAD

Open the STAD breakdown →