LARP1B

Across TCGA cell cohorts, LARP1B mutation is significantly associated with the drug of many other genes, with 16 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LARP1B-associated genes across cancer lineages are 630600, KRAS (G12C) Inhibitor-12, and Ispinesib Mesylate. Each is linked with LARP1B in more than 1 cancer types. Because this analysis shows association rather than direction, both LARP1B-to-partner and partner-to-LARP1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 630600 grouped by LARP1B-low versus LARP1B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LARP1B→partner) and Y-score (partner→LARP1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	630600 →	+0.601	+2.871	.042	.021	3	1
LARGE_INTESTINE	KRAS (G12C) Inhibitor-12 →	+0.499	+2.868	.035	.022	3	1
LARGE_INTESTINE	Ispinesib Mesylate →	+0.662	+2.874	.032	.021	3	1
LARGE_INTESTINE	CDK9_5038 →	+0.571	+3.129	.028	.014	2	1
LARGE_INTESTINE	ULK1_4989 →	+0.741	+2.871	.017	.021	2	1
LARGE_INTESTINE	Oxaliplatin →	+0.552	+2.678	.027	.037	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

630600 by LARP1B expression — LARGE_INTESTINE

Explore this box plot interactively →