LAPTM4B

Across TCGA patient cohorts, LAPTM4B protein abundance is significantly associated with the RNA expression of many other genes, with 376 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible LAPTM4B-associated genes across cancer lineages are DESI1, CYP27B1, and LPCAT3. Each is linked with LAPTM4B in more than 1 cancer types. Because this analysis shows association rather than direction, both LAPTM4B-to-partner and partner-to-LAPTM4B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LAPTM4B versus DESI1 in OV, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LAPTM4B→partner) and Y-score (partner→LAPTM4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DESI1 →	-0.474	-1.101	.002	<.001	3	1
OV	CYP27B1 →	-0.370	-0.698	.002	.007	3	1
OV	LPCAT3 →	+0.761	+0.901	.002	<.001	3	1
OV	GATA5 →	+0.876	+0.607	<.001	.005	3	1
OV	IDH1 →	+1.009	+1.057	.002	.001	3	1
OV	CBR4 →	-0.688	-0.800	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 376 associations by consensus.

LAPTM4B vs DESI1 — OV

Explore this scatter interactively →