LANCL3

Across TCGA patient cohorts, LANCL3 mutation is significantly associated with the RNA expression of many other genes, with 855 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LANCL3-associated genes across cancer lineages are RNU6-147P, RNU6-15P, and MIR4716. Each is linked with LANCL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both LANCL3-to-partner and partner-to-LANCL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-147P grouped by LANCL3-low versus LANCL3-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LANCL3→partner) and Y-score (partner→LANCL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-147P →	+0.462	+5.212	.004	.007	3	2
COAD	RNU6-15P →	+0.468	+5.145	.001	.007	3	2
COAD	MIR4716 →	+1.398	+6.547	<.001	.001	3	2
UCEC	CD79A →	+1.315	+3.724	.001	<.001	3	2
HNSC	MIR5692C1 →	+0.423	+5.578	<.001	.004	3	2
LUSC	RNU6-668P →	+0.262	+5.309	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 855 associations by consensus.

RNU6-147P by LANCL3 expression — COAD

Explore this box plot interactively →