LANCL1-AS1

Across TCGA pan-cancer cohorts, LANCL1-AS1 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated LANCL1-AS1 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher LANCL1-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LANCL1-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and SKCM show a favorable association.

UCEC, UCS, and UVM are the cancer types where LANCL1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	0.561	0.733	<.001	66	view →
UCS	DFS	Quartile	II,III,IV	0.690	0.107	.001	50	view →
UVM	DFS	Tertile	All	0.336	1.000	.003	35	view →
SKCM	OS	Tertile	III,IV	0.766	0.596	.010	28	view →
KICH	OS	Quartile	All	0.698	1.000	.011	28	view →
LUSC	DFS	Median	III,IV	0.372	0.871	.007	19	view →
ACC	DFS	Median	IV	0.123	0.563	<.001	17	view →
STAD	DFS	Quartile	IV	0.135	0.667	.005	15	view →
CHOL	DFS	Tertile	II,III,IV	0.099	0.754	.006	11	view →
COAD	OS	Median	All	0.442	0.702	.004	11	view →
READ	OS	Median	All	0.767	0.501	.009	8	view →
TGCT	DFS	Median	All	0.916	0.746	.021	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

LANCL1-AS1–UCEC (DFS)

Open the UCEC breakdown →