LANCL1-AS1

Across TCGA pan-cancer cohorts, LANCL1-AS1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of LANCL1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where LANCL1-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types LANCL1-AS1 is over-expressed in tumor, although a few such as LUAD and THCA show the opposite, repressed pattern.

LUAD, THCA, and LUSC are the cancer types where LANCL1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LANCL1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	III,IV	−3.496	<.001	11	view →
THCA	Male	II,III,IV	−0.641	<.001	11	view →
LUSC	All	III,IV	−3.048	<.001	9	view →
UCEC	All	II,III,IV	−0.388	<.001	6	view →
BRCA	All	All	−0.220	<.001	6	view →
KICH	All	All	−0.231	<.001	5	view →
LIHC	All	All	+0.098	.001	3	view →
KIRC	All	All	+0.097	.001	3	view →
HNSC	Male	All	−0.735	.016	2	view →
BLCA	Male	IV	−0.575	.003	2	view →
CHOL	All	All	+0.393	.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

LANCL1-AS1–LUAD

Open the LUAD breakdown →