LAMP5

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LAMP5 protein abundance is significantly associated with the RNA expression of many other genes, with 4,766 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LAMP5-associated genes across cancer lineages are OLFM1, FEZF2, and PBK. Each is linked with LAMP5 in more than 2 cancer types. Because this analysis shows association rather than direction, both LAMP5-to-partner and partner-to-LAMP5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LAMP5 versus OLFM1 in GBM, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LAMP5→partner) and Y-score (partner→LAMP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMOLFM1 →+1.385+0.923<.001<.00132
GBMFEZF2 →+1.243+1.148<.001<.00132
OVPBK →-1.405-1.773.007.00932
GBMDPP10 →+1.425+0.766<.001<.00132
GBMUPP1 →-0.809-0.681.001<.00132
GBMKCTD16 →+0.738+0.780<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,766 associations by consensus.

LAMP5 vs OLFM1 — GBM

Per-sample scatter of LAMP5 vs OLFM1 in GBM (Pearson r = 0.42).

Explore this scatter interactively →

Exploration