LAMP3

Across TCGA patient cohorts, LAMP3 protein abundance is significantly associated with the RNA expression of many other genes, with 7,585 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LAMP3-associated genes across cancer lineages are STX11, PKD2L1, and NR5A2. Each is linked with LAMP3 in more than 3 cancer types. Because this analysis shows association rather than direction, both LAMP3-to-partner and partner-to-LAMP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LAMP3 versus STX11 in OV, with a Pearson correlation of 0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LAMP3→partner) and Y-score (partner→LAMP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	STX11 →	+0.811	+1.815	<.001	.001	3	4
LSCC	PKD2L1 →	+0.605	+0.522	<.001	<.001	3	3
OV	NR5A2 →	+0.642	+2.147	<.001	.004	3	3
OV	CSF3R →	+1.275	+1.375	<.001	.001	3	3
OV	RAMP3 →	+1.323	+2.110	.004	.009	2	4
LSCC	FCN3 →	+1.711	+0.784	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,585 associations by consensus.

LAMP3 vs STX11 — OV

Explore this scatter interactively →