Across TCGA patient cohorts, LAMP1 mutation is significantly associated with the RNA expression of many other genes, with 780 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LAMP1-associated genes across cancer lineages are RN7SL248P, MIR8053, and FARSBP1. Each is linked with LAMP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both LAMP1-to-partner and partner-to-LAMP1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LAMP1→partner) and Y-score (partner→LAMP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.084	+3.606	<.001	.002	3	2
COAD	MIR8053 →	+0.277	+4.399	<.001	.006	3	2
LUAD	FARSBP1 →	+0.031	+5.984	<.001	.002	3	2
LUAD	RN7SL51P →	+0.260	+5.481	<.001	.005	3	2
BLCA	MIR3139 →	+0.626	+4.568	<.001	.004	3	2
BLCA	OR8D2 →	+0.068	+5.618	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 780 associations by consensus.

Exploration

LAMP1 survival (RNA) · tumor vs normal (RNA) · all LAMP1 data types