LAMB4

Across TCGA patient cohorts, LAMB4 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,156 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LAMB4-associated GO terms across cancer lineages are Focal adhesion assembly, Body morphogenesis, and Respiratory system development. Each is linked with LAMB4 in more than 22 cancer types. Because this analysis shows association rather than direction, both LAMB4-to-partner and partner-to-LAMB4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Focal adhesion assembly grouped by LAMB4-low versus LAMB4-high in TGCT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LAMB4→partner) and Y-score (partner→LAMB4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	Focal adhesion assembly →	+0.073	+0.289	<.001	<.001	3	23
STAD	Body morphogenesis →	+0.060	+0.134	<.001	<.001	3	22
STAD	Respiratory system development →	+0.053	+0.137	<.001	<.001	3	22
STAD	Lamellipodium organization →	+0.060	+0.149	<.001	<.001	3	21
STAD	Cell-substrate junction organization →	+0.069	+0.147	<.001	<.001	3	21
SCLC	Regulation of cell-substrate junction organization →	+0.102	+0.209	.001	.001	1	23

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,156 associations by consensus.

Focal adhesion assembly by LAMB4 expression — TGCT

Explore this box plot interactively →