LAMB4

Across TCGA patient cohorts, LAMB4 protein abundance is significantly associated with the RNA expression of many other genes, with 14,359 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LAMB4-associated genes across cancer lineages are MGME1, IL2RA, and INSYN2B. Each is linked with LAMB4 in more than 1 cancer types. Because this analysis shows association rather than direction, both LAMB4-to-partner and partner-to-LAMB4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LAMB4 versus MGME1 in LSCC, with a Pearson correlation of -0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LAMB4→partner) and Y-score (partner→LAMB4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MGME1 →	-0.523	-0.722	.006	.006	3	2
UCEC	IL2RA →	+1.068	+0.929	.005	.001	3	2
LSCC	INSYN2B →	+0.868	+1.281	<.001	<.001	3	2
LSCC	GIMAP1 →	+0.680	+1.107	<.001	<.001	3	2
UCEC	GOLGA5P1 →	+1.170	+0.829	.003	.002	3	2
OV	MRGBP →	-0.738	-1.085	.004	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,359 associations by consensus.

LAMB4 vs MGME1 — LSCC

Explore this scatter interactively →