LAMB4

Across TCGA cell cohorts, LAMB4 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,009 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible LAMB4-associated GO terms across cancer lineages are Energy derivation by oxidation of organic compounds, Positive regulation of microtubule polymerization, and Positive regulation of DNA-templated transcription, elongation. Each is linked with LAMB4 in more than 5 cancer types. Because this analysis shows association rather than direction, both LAMB4-to-partner and partner-to-LAMB4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Energy derivation by oxidation of organic compounds grouped by LAMB4-low versus LAMB4-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LAMB4→partner) and Y-score (partner→LAMB4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Energy derivation by oxidation of organic compounds →	+0.047	+0.165	.001	.006	3	5
LUNG_SCLC	Positive regulation of microtubule polymerization →	+0.087	+0.314	<.001	.001	3	5
LUNG_SCLC	Positive regulation of DNA-templated transcription, elongation →	+0.045	+0.313	.003	.001	3	5
LUNG_SCLC	Positive regulation of transcription elongation by RNA polymerase II →	+0.041	+0.321	.005	.001	3	5
LARGE_INTESTINE	Regulation of cellular component size →	+0.035	+0.078	<.001	.006	3	5
SKIN	Endosomal lumen acidification →	+0.088	+0.330	.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,009 associations by consensus.

Energy derivation by oxidation of organic compounds by LAMB4 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →