LAMA3

Across TCGA patient cohorts, LAMA3 protein abundance is significantly associated with the RNA expression of many other genes, with 10,627 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible LAMA3-associated genes across cancer lineages are LAMC2, CAV2, and ABLIM3. Each is linked with LAMA3 in more than 8 cancer types. Because this analysis shows association rather than direction, both LAMA3-to-partner and partner-to-LAMA3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LAMA3 versus LAMC2 in LSCC, with a Pearson correlation of 0.75.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LAMA3→partner) and Y-score (partner→LAMA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	LAMC2 →	+1.977	+0.970	<.001	<.001	3	9
LSCC	CAV2 →	+1.055	+0.845	<.001	<.001	3	7
BRCA	ABLIM3 →	+1.147	+0.590	<.001	<.001	3	6
OV	AHNAK2 →	+2.147	+1.231	<.001	<.001	2	7
OV	LAMB3 →	+2.097	+1.454	<.001	<.001	3	6
OV	ITGA3 →	+1.288	+1.020	.001	.005	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,627 associations by consensus.

LAMA3 vs LAMC2 — LSCC

Explore this scatter interactively →