LALBA

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, LALBA Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated LALBA data layer compared with 11 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher LALBA Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated LALBA expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

LUAD, COAD, and UCEC are the cancer types where LALBA Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUADDFSMedianAll0.0490.814<.0016view →
COADDFSMedianAll0.1720.693.0443view →
UCECDFSMedianII,III,IV1.0000.443.0422view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

LALBA–LUAD (DFS)

Kaplan–Meier survival curve for LALBA mutant vs wild-type samples in LUAD.

Open the LUAD breakdown →

Exploration