LAIR2

Across TCGA patient cohorts, LAIR2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,980 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LAIR2-associated proteins across cancer lineages are SEPTIN1, HCLS1, and IKZF1_S445. Each is linked with LAIR2 in more than 8 cancer types. Because this analysis shows association rather than direction, both LAIR2-to-partner and partner-to-LAIR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LAIR2 versus SEPTIN1 in GBM, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LAIR2→partner) and Y-score (partner→LAIR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SEPTIN1 →	+0.726	+0.450	.007	<.001	3	9
GBM	HCLS1 →	+0.680	+0.410	<.001	<.001	3	9
BRCA	IKZF1_S445 →	+1.063	+0.728	<.001	<.001	3	9
GBM	LSP1 →	+0.699	+0.366	<.001	<.001	3	9
GBM	ARHGAP45 →	+0.604	+0.386	<.001	<.001	3	8
GBM	PLCB2 →	+0.558	+0.426	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,980 associations by consensus.

LAIR2 vs SEPTIN1 — GBM

Explore this scatter interactively →