L3MBTL2

Across TCGA patient cohorts, L3MBTL2 protein abundance is significantly associated with the RNA expression of many other genes, with 14,376 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible L3MBTL2-associated genes across cancer lineages are MGA, OIP5, and CCDC150. Each is linked with L3MBTL2 in more than 3 cancer types. Because this analysis shows association rather than direction, both L3MBTL2-to-partner and partner-to-L3MBTL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, L3MBTL2 versus MGA in LSCC, with a Pearson correlation of 0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (L3MBTL2→partner) and Y-score (partner→L3MBTL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MGA →	+0.421	+0.293	<.001	<.001	3	4
BRCA	OIP5 →	+0.591	+0.166	<.001	.003	3	4
LSCC	CCDC150 →	+0.890	+0.427	<.001	<.001	3	4
HNSC	SRSF2 →	+0.397	+0.388	.001	<.001	3	4
BRCA	SKA3 →	+1.234	+0.309	<.001	<.001	3	4
PDAC	RAB31 →	-1.083	-0.764	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,376 associations by consensus.

L3MBTL2 vs MGA — LSCC

Explore this scatter interactively →