L1TD1

Across TCGA cell cohorts, L1TD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,207 significant associations in total. BONE shows the largest number of these associations.

The most reproducible L1TD1-associated GO terms across cancer lineages are Regulation of ossification, Regulation of bone mineralization, and Regulation of vasculature development. Each is linked with L1TD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both L1TD1-to-partner and partner-to-L1TD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of ossification grouped by L1TD1-low versus L1TD1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (L1TD1→partner) and Y-score (partner→L1TD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of ossification →	-0.091	-2.376	<.001	<.001	3	3
BONE	Regulation of bone mineralization →	-0.126	-2.483	<.001	<.001	3	3
BONE	Regulation of vasculature development →	-0.081	-2.081	.003	<.001	3	3
BONE	Negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II →	-1.522	-2.027	<.001	.005	3	3
BONE	Protein localization to nucleus →	+0.040	+2.195	.001	.001	3	3
BONE	Regulation of angiogenesis →	-0.107	-2.200	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,207 associations by consensus.

Regulation of ossification by L1TD1 expression — BONE

Explore this box plot interactively →