Across TCGA patient cohorts, L1CAM RNA expression is significantly associated with the protein abundance of many other proteins, with 13,324 significant associations in total. GBM shows the largest number of these associations.

The most reproducible L1CAM-associated proteins across cancer lineages are FAM120A, UCHL1, and CEP170. Each is linked with L1CAM in more than 5 cancer types. Because this analysis shows association rather than direction, both L1CAM-to-partner and partner-to-L1CAM results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (L1CAM→partner) and Y-score (partner→L1CAM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FAM120A →	-0.201	-1.545	<.001	<.001	3	6
UCEC	UCHL1 →	+1.042	+1.346	<.001	<.001	3	5
CCRCC	CEP170 →	+0.304	+1.104	<.001	.004	2	6
BRCA	IGF2BP2 →	+0.646	+0.735	<.001	<.001	3	5
CCRCC	MAP4_S696 →	+0.616	+1.124	<.001	.003	3	5
GBM	RBM47 →	-0.406	-1.199	.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,324 associations by consensus.

Exploration

L1CAM survival (RNA) · tumor vs normal (RNA) · all L1CAM data types