KYNUP3

Across TCGA patient cohorts, KYNUP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,707 significant associations in total. STAD shows the largest number of these associations.

The most reproducible KYNUP3-associated GO terms across cancer lineages are CD4-positive, alpha-beta T cell activation, Regulation of antigen receptor-mediated signaling pathway, and Positive regulation of plasma membrane bounded cell projection assembly. Each is linked with KYNUP3 in more than 5 cancer types. Because this analysis shows association rather than direction, both KYNUP3-to-partner and partner-to-KYNUP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD4-positive, alpha-beta T cell activation grouped by KYNUP3-low versus KYNUP3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KYNUP3→partner) and Y-score (partner→KYNUP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	CD4-positive, alpha-beta T cell activation →	+0.091	+0.010	<.001	<.001	3	6
STAD	Regulation of antigen receptor-mediated signaling pathway →	+0.104	+0.008	<.001	<.001	3	6
STAD	Positive regulation of plasma membrane bounded cell projection assembly →	+0.088	+0.009	<.001	<.001	3	5
LUSC	Natural killer cell differentiation →	+0.083	+0.005	<.001	<.001	3	5
STAD	Positive regulation of leukocyte cell-cell adhesion →	+0.101	+0.010	<.001	<.001	3	5
STAD	Positive regulation of hemopoiesis →	+0.092	+0.010	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,707 associations by consensus.

CD4-positive, alpha-beta T cell activation by KYNUP3 expression — STAD

Explore this box plot interactively →