Q-omics provides the consensus-scored KYNUP3 profile across patient tissues and cancer cell-line models. KYNUP3 expression is associated with patient survival in 6 of 34 cancer types, with the highest sampling consensus in COAD. Additionally, KYNUP3 RNA expression shows 5,707 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight COAD, and STAD as cancer lineages where KYNUP3 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes KYNUP3 survival associations across molecular data types. KYNUP3 RNA expression shows survival associations in the most cancer types (6). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

KYNUP3 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	6	COAD (45)	view →

This table ranks reproducible KYNUP3 RNA expression–survival associations across cancer types. High KYNUP3 expression shows unfavorable associations in COAD, HNSC, LIHC, KIRC, LUAD and SKCM. The COAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify COAD as the clearest survival context for KYNUP3 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	All	0.035	0.791	<.001	45	view →
HNSC	DFS	Tertile	All	0.146	0.664	<.001	33	view →
LIHC	OS	Tertile	II,III,IV	0.226	0.769	.008	27	view →
KIRC	DFS	Tertile	IV	0.167	0.605	<.001	18	view →
LUAD	OS	Tertile	II,III,IV	0.150	0.677	.008	18	view →
SKCM	OS	Tertile	III,IV	0.173	0.698	.002	12	view →

Pink = unfavorable, green = favorable. all 6 lineages →

KYNUP3-COAD (DFS)

Kaplan–Meier survival curve for KYNUP3 RNA expression in COAD: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with KYNUP3 in patient tissues and cancer cell lines. In patient samples, KYNUP3 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Function (RNA)	5,707	STAD (5242)	view →
RNA	2,968	STAD (806)	view →