KYNU

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KYNU RNA expression is significantly associated with the protein abundance of many other proteins, with 19,342 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KYNU-associated proteins across cancer lineages are MYO1F, NCF2, and NCF4. Each is linked with KYNU in more than 8 cancer types. Because this analysis shows association rather than direction, both KYNU-to-partner and partner-to-KYNU results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KYNU versus MYO1F in GBM, with a Pearson correlation of 0.88.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KYNU→partner) and Y-score (partner→KYNU) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMMYO1F →+0.869+0.960<.001<.00139
GBMNCF2 →+0.958+0.822<.001<.00139
GBMNCF4 →+0.934+0.899<.001<.00139
GBMDOCK8 →+0.667+0.948<.001<.00139
GBMFERMT3 →+0.887+0.979<.001<.00139
GBMFMNL1 →+0.839+0.948<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 19,342 associations by consensus.

KYNU vs MYO1F — GBM

Per-sample scatter of KYNU vs MYO1F in GBM (Pearson r = 0.88).

Explore this scatter interactively →

Exploration