KYAT1

Across TCGA patient cohorts, KYAT1 mutation is significantly associated with the RNA expression of many other genes, with 2,605 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KYAT1-associated genes across cancer lineages are PATL1, MICU1, and RNA5SP89. Each is linked with KYAT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both KYAT1-to-partner and partner-to-KYAT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PATL1 grouped by KYAT1-low versus KYAT1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KYAT1→partner) and Y-score (partner→KYAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PATL1 →	+0.484	+3.470	.003	.002	3	3
SKCM	MICU1 →	+0.519	+3.234	.003	.008	3	3
UCEC	RNA5SP89 →	+0.123	+3.292	.001	.003	3	3
UCEC	RPL23AP7 →	+0.432	+3.247	.001	<.001	3	3
SKCM	MIR6769B →	+0.197	+5.058	<.001	.001	3	2
UCEC	RNU6-6P →	+0.383	+1.629	.004	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,605 associations by consensus.

PATL1 by KYAT1 expression — UCEC

Explore this box plot interactively →