KYAT1

Across TCGA pan-cancer cohorts, KYAT1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated KYAT1 data layer compared with 4 for mutation status.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher KYAT1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated KYAT1 expression acts as an unfavorable survival marker, although some lineages such as LGG and KIRC show a favorable association.

ACC, COAD, and LGG are the cancer types where KYAT1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.421	0.742	<.001	102	view →
COAD	OS	Tertile	II,III,IV	0.481	0.690	.001	88	view →
LGG	OS	Median	All	0.888	0.731	<.001	45	view →
KIRC	DFS	Tertile	All	0.840	0.636	<.001	35	view →
READ	DFS	Quartile	II,III,IV	1.000	0.372	.002	34	view →
GBM	DFS	Median	All	0.311	0.199	.005	30	view →
OV	OS	Quartile	All	0.300	0.441	.004	20	view →
LIHC	DFS	Median	All	0.379	0.491	.009	19	view →
LUAD	DFS	Median	All	0.618	0.707	.006	17	view →
UCEC	DFS	Median	III,IV	0.699	0.452	.019	16	view →
STAD	DFS	Median	IV	0.155	0.565	.009	15	view →
HNSC	OS	Quartile	III,IV	0.615	0.885	.004	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

KYAT1–ACC (DFS)

Open the ACC breakdown →